Sinopse

Suitable for advanced undergraduates and postgraduates, "Understanding Bioinformatics" provides a definitive guide to this vibrant and evolving discipline. This book takes a conceptual approach. It guides the reader from first principles through to an understanding of the computational techniques and the key algorithms. "Understanding Bioinformatics" is an invaluable companion for students from their first encounter with the subject through to more advanced studies. This book is divided into seven parts, with the opening part introducing the basics of nucleic acids, proteins and databases. Subsequent parts are divided into ´Applications´ and ´Theory´ Chapters, allowing readers to focus their attention effectively.In each section, the Applications Chapter provides a fast and straightforward route to understanding the main concepts and ´getting started´. Each of these is then followed by Theory Chapters which give greater detail and present the underlying mathematics. In Part 2, Sequence Alignments, the Applications Chapter shows the reader how to get started on producing and analyzing sequence alignments, and using sequences for database searching, while the next two chapters look closely at the more advanced techniques and the mathematical algorithms involved. The Part 3 covers evolutionary processes and shows how bioinformatics can be used to help build phylogenetic trees. Part 4 looks at the characteristics of whole genomes. In Parts 5 and 6 the focus turns to secondary and

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